Vital signs and impaired cognition in older emergency department patients: The APOP study.
Jacinta A LuckeJelle de GelderLaura C BlomaardChristian HeringhausJelmer AlsmaStephanie C E Klein Nagelvoort SchuitAnniek BrinkSander AntenGerard J BlauwBas de GrootSimon P MooijaartPublished in: PloS one (2019)
Abnormal vital signs associated with decreased brain perfusion and oxygenation are also associated with cognitive impairment in older ED patients. This may partially be explained by the association between disease severity and delirium, but also by acute disturbance of brain perfusion and oxygenation. Future studies should establish whether normalization of vital signs will also acutely improve cognition.
Keyphrases
- emergency department
- end stage renal disease
- white matter
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- resting state
- magnetic resonance imaging
- intensive care unit
- functional connectivity
- liver failure
- computed tomography
- mild cognitive impairment
- middle aged
- multiple sclerosis
- patient reported outcomes
- contrast enhanced
- blood flow
- current status
- brain injury
- adverse drug