Inter-related effects of insulin resistance, hyperandrogenism, sympathetic dysfunction and chronic inflammation in PCOS.

Soulmaz ShorakaeSanjeeva RanasinhaSally AbellGavin LambertElisabeth LambertBarbora de CourtenHelena J Teede

Published in: Clinical endocrinology (2018)

Sympathetic dysfunction and hyperandrogenism are significantly associated with PCOS. Chronic low-grade inflammation potentially mediates the effect of sympathetic dysfunction on hyperandrogenism and insulin resistance.

Keyphrases

polycystic ovary syndrome
insulin resistance
oxidative stress
low grade
adipose tissue
high fat diet
metabolic syndrome
skeletal muscle
high grade
type diabetes
high fat diet induced
drug induced
weight loss