Sex-driven modifiers of Alzheimer risk: A multimodality brain imaging study.
Aneela RahmanEva SchelbaumKatherine HoffmanIvan DiazHollie HristovRandolph AndrewsSteven JettHande JacksonAndrea LeeHarini SarvaSilky PahlajaniDawn MatthewsJonathan P DykeMony J de LeonRichard S IsaacsonRoberta D BrintonLisa MosconiPublished in: Neurology (2020)
Hormonal risk factors, in particular menopause, predict AD endophenotype in middle-aged women. These findings suggest that the window of opportunity for AD preventive interventions in women is early in the endocrine aging process.