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Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.

Qilu FangWenxiu XinLiangsheng ChenYuxuan FuYajun QiHaiying DingLuo Fang
Published in: PloS one (2023)
This study illustrated that CAPE restrained FGFR1 activation and nuclear transfer through MD2/FGFR1 complex inhibition and showed good inhibitory effects on the metastasis of breast cancer cells.
Keyphrases
  • breast cancer cells
  • molecular dynamics
  • south africa
  • signaling pathway