Effect of Weight Gain and Weight Loss on In Vivo Colonocyte Proliferation Rate in People with Obesity.

Faidon MagkosShelby SullivanMark FitchGordon SmithElisa FabbriniBettina MittendorferMarc HellersteinSamuel Klein

Published in: Obesity (Silver Spring, Md.) (2018)

A high-calorie diet and weight gain increase, whereas a low-calorie diet and weight loss decrease, in vivo colonocyte proliferation rate in people with obesity. These results suggest that changes in energy balance influence the risk of developing colon cancer in people with obesity by regulating colonic mucosal growth rates.

Keyphrases

weight loss
weight gain
bariatric surgery
birth weight
roux en y gastric bypass
gastric bypass
signaling pathway
body mass index
glycemic control
obese patients
metabolic syndrome
physical activity
high fat diet induced