Outcomes of SDHB pathogenic variant carriers: A systematic review and meta-analysis.

Dahlia F DavidoffRichard De Abreu LourencoVenessa H M TsangDiana E BennRoderick J Clifton-Bligh

Published in: The Journal of clinical endocrinology and metabolism (2024)

Penetrance for PPGL in SDHB PV carriers increases linearly with age. Affected carriers are at risk of developing and dying from metastatic disease, or of developing second tumors. Lifelong surveillance is appropriate.

Keyphrases

squamous cell carcinoma
public health
small cell lung cancer
palliative care
type diabetes
adipose tissue