Research progress of implantation materials and its biological evaluation.

With the development of modern material science, life science and medical science, implantation materials are wide employed in clinical fields. In recent years, these materials have also evolved from the inert supports or functional substitutes to the bioactive materials able to trigger or promote the regenerative potential of tissues. Reasonable biological evaluation of implantation materials is that the premise to make sure their safe application in clinical practice. With the continual development of implantation materials and therefore the emergence of new implantation materials, new challenges to biological evaluation have been presented. In this paper, the research progress of implantation materials, the progress of biological evaluation methods, and also the characteristics of biocompatibility evaluation for novel implantation materials, like animal-derived implantation materials, nerve contact implantation materials, nanomaterials and tissue engineered medical products were reviewed, that provided references for the rational biological evaluation of implantable materials.