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RHD genotype and zygosity analysis in the Chinese Southern Han D+, D- and D variant donors using the multiplex ligation-dependent probe amplification assay.

Yanli JiH LuoJ Z WenL Haer-WigmanB VeldhuisenL WeiZ WangP LigthartM Lodén-van StraatenY S FuC E van der SchootG P Luo
Published in: Vox sanguinis (2017)
The RH-MLPA assay correctly identified the common RHD variant alleles in the Chinese population. However, DNA sequencing was required to identify certain alleles; probes to detect these alleles should be added into the assay.
Keyphrases
  • high throughput
  • nucleic acid
  • single molecule
  • single cell
  • living cells
  • circulating tumor
  • cell free
  • fluorescence imaging
  • photodynamic therapy