The pretreatment of rats with nebivolol ameliorates bladder contractile dysfunction caused by ischemia-reperfusion injury.

Hande Özge Altunkaynak-Çamca Nuray Yazihan

Published in: Lower urinary tract symptoms (2020)

The present study indicates that pretreatment of rats with nebivolol (0.4 mg/kg) could improve bladder contractile dysfunction caused by IR injury through suppression of increased oxidative stress and IL-6 levels.

Keyphrases

oxidative stress
ischemia reperfusion injury
spinal cord injury
skeletal muscle
dna damage
diabetic rats
smooth muscle
induced apoptosis
urinary tract
mouse model
signaling pathway
heat shock