Second allogeneic transplantation using umbilical cord blood for a patient with relapsed ALK+ anaplastic large cell lymphoma after allogeneic bone marrow transplantation in the era of ALK inhibitors: A case report.
Sumiko SaitoHaruko TashiroRitsu SumiyoshiTakuji MatsuoTadashi YamamotoKensuke MatsumotoJun OoiNaoki ShirafujiPublished in: Medicine (2021)
Both ALK inhibitors demonstrated drastic efficacy for our patient who had chemotherapy- and BV-resistant ALK+ ALCL with leukemic presentation. Alectinib showed less gastro-intestinal toxicity than crizotinib and the patient was able to take it even at the relatively early phase of stem cell transplantation.
Keyphrases
- stem cell transplantation
- bone marrow
- advanced non small cell lung cancer
- case report
- mesenchymal stem cells
- high dose
- umbilical cord
- cell therapy
- acute myeloid leukemia
- diffuse large b cell lymphoma
- acute lymphoblastic leukemia
- oxidative stress
- single cell
- epidermal growth factor receptor
- squamous cell carcinoma
- low dose
- radiation therapy