Top-down approach is possible strategy for predicting breakthrough fUTIs and renal scars in infants.
Shina KawaiTakahiro KanaiTaiju HyugaShigeru NakamuraJun AoyagiTakane ItoTakashi SaitoJun OdakaRieko FurukawaToshinori AiharaHideo NakaiPublished in: Pediatrics international : official journal of the Japan Pediatric Society (2018)
The top-down approach is a possible method for predicting r-fUTI in infants and does not miss clinically significant VUR. Also, given that the prevalence of r-fUTI was 5% regardless of the presence of defects on acute-phase DMSA, then, in conjunction with genital hygiene and CAP, acute-phase DMSA might be unnecessary if chronic-phase DMSA is performed for all patients to detect renal scar.