Hallmarks in prostate cancer imaging with Ga68-PSMA-11-PET/CT with reference to detection limits and quantitative properties.

Alejandro Sanchez-CrespoEmma JussingAnn-Charlotte BjörklundKatja Pokrovskaja Tamm

Published in: EJNMMI research (2018)

Ga68-PSMA-11-PET detects a small number of LNCaP cells even when they are mixed in a population of non-PSMA expressing cells and in the presence of background. The obtained image detection limits and characteristic quantification properties of Ga68-PSMA-11-PET/CT are essential hallmarks for the individualization of patient management. The use of the standardized uptake value for Ga68-PSMA-11-PET/CT image quantification should be precluded.

Keyphrases

pet ct
induced apoptosis
prostate cancer
positron emission tomography
high resolution
deep learning
endoplasmic reticulum stress
computed tomography
label free
cell proliferation
signaling pathway
case report
pet imaging