G-CSF promotes the viability and angiogenesis of injured liver via direct effects on the liver cells.

Zifeng LiuGuiling ZhangJing ChenJingjing TongHongmin WangJing ChenDong YangJin-Hua Hu

Published in: Molecular biology reports (2022)

G-CSF promotes injured liver viability and angiogenesis by directly affecting injured liver cells via the AKT and ERK signalling pathways. These findings improve our understanding of the role of G-CSF in recovery from LF.

Keyphrases

induced apoptosis
signaling pathway
cell cycle arrest
endothelial cells
cell proliferation
vascular endothelial growth factor
oxidative stress
cell death
cerebrospinal fluid
wound healing