Heat-shock protein 90α protects NME1 against degradation and suppresses metastasis of breast cancer.

Yanchao ZhangGuomeng ZhaoLiting YuXindong WangYao MengJinlei MaoZiyi FuYongmei YinJinyao LiXun WangChangying Guo

Published in: British journal of cancer (2023)

These results not only reveal a new mechanism of NME1 degradation but also pave the way for the development of new and effective approaches to metastatic cancer therapy.

Keyphrases

heat shock protein
cancer therapy
heat shock
squamous cell carcinoma
drug delivery
small cell lung cancer
signaling pathway
genome wide
single cell
gene expression
dna methylation
heat stress