Role of upper abdominal reirradiation for gastrointestinal malignancies: a systematic review of cumulative dose, toxicity, and outcomes on behalf of the Re-Irradiation Working Group of the Italian Association of Radiotherapy and Clinical Oncology (AIRO).

Luciana Caravatta Francesco Fiorica Consuelo Rosa Luca Boldrini Anna Rita Alitto Alessia Nardangeli Francesco Dionisi Lavinia Bianco Fernando Munoz Marco Lupattelli Giovanna Mantello Domenico Genovesi Mariangela Massaccesinull null

Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2019)

Due to limited evidence as a result of the retrospective design of the majority of the studies, our review suggests that upper abdominal Re‑I is effective in terms of local control and palliation, with a moderate rate of severe toxicities.

Keyphrases

early stage
radiation induced
palliative care
radiation therapy
oxidative stress
high intensity
locally advanced
early onset
squamous cell carcinoma
metabolic syndrome
adipose tissue
rectal cancer
glycemic control
oxide nanoparticles