Prevalence of non-thyroidal illness syndrome in COPD exacerbation and effect of hypoxaemia and hypercapnia on thyroid functions.

Aziz Gümüş Songül Özyurt Neslihan Ozcelik Bilge Yılmaz Kara

Published in: The clinical respiratory journal (2020)

NTIS is a very common condition during AECOPD. We believe that hypoxemia causing functional impairment in the hypothalamic-pituitary-thyroid axis is the main mechanism in NTIS development and hypercapnia disrupts freeT3 and freeT4 production and secretion.

Keyphrases

cystic fibrosis
lung function
chronic obstructive pulmonary disease
risk factors
case report
growth hormone
air pollution
mechanical ventilation
respiratory failure