A Phase I/II Study of Veliparib (ABT-888) in Combination with 5-Fluorouracil and Oxaliplatin in Patients with Metastatic Pancreatic Cancer.
Michael J PishvaianHongkun WangAiwu Ruth HeJimmy J HwangBrandon G SmagloSunnie S KimBenjamin A WeinbergLouis M WeinerJohn L MarshallJonathan R BrodyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
The combination of veliparib and FOLFOX was safe for patients with metastatic PDAC and showed promising activity particularly in patients with platinum-naïve disease that harbors a pathogenic HR-DDR mutation.
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