β-Amyloid Load on PET Along the Continuum of Dementia With Lewy Bodies.
Patricia Diaz-GalvanScott A PrzybelskiTimothy G LesnickChristopher G SchwarzMatthew L SenjemJeffrey L GunterClifford R JackHoon-Ki Paul MinManoj JainToji MiyagawaLeah K ForsbergJulie A FieldsRodolfo SavicaJonathan Graff-RadfordDavid T JonesHugo BothaErik K St LouisDavid S KnopmanVijay K RamananOwen RossNeill Graff-RadfordGregory S DayGourisankar GhoshTanis J FermanRonald C PetersenVal J LoweBradley F BoeveKejal KantarciPublished in: Neurology (2023)
ε4 non-carriers and women tended to have higher amyloid-β levels than men as they got older. These findings have important implications in targeting patients within the DLB continuum for clinical trials of disease-modifying therapies.
Keyphrases
- clinical trial
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prognostic factors
- mild cognitive impairment
- metabolic syndrome
- pregnant women
- drug delivery
- cancer therapy
- positron emission tomography
- pet ct
- polycystic ovary syndrome
- pregnancy outcomes
- open label
- cognitive impairment
- pet imaging
- adipose tissue
- skeletal muscle
- phase ii
- patient reported