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Not only mutations but also tumorigenesis can be substantially attributed to DNA damage from reactive oxygen species in RUNX1::RUNX1T1-fusion-positive acute myeloid leukemia.

Jeffrey D MandellJ Nicholas FiskEthan CyrenneMina L XuVincent L CannataroJeffrey P Townsend
Published in: Leukemia (2022)
Keyphrases
  • dna damage
  • reactive oxygen species
  • acute myeloid leukemia
  • transcription factor
  • oxidative stress
  • dna repair
  • acute lymphoblastic leukemia