Design, synthesis, molecular docking study, and antibacterial evaluation of some new fluoroquinolone analogues bearing a quinazolinone moiety.
Maryam NorouzbahariSomayeh SalarinejadMümtaz GüranGizem ŞanlıtürkZahra EmamgholipourHamid Reza BijanzadehMahsa ToolabiAlireza ForoumadiPublished in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2020)
The results of the current study demonstrated that the novel ciprofloxacin and sarafloxacin derivatives synthesized here have promising antibacterial activities. Particularly, compounds 5d and 5i have potential for wider antibacterial applications following further analysis.