Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA).

Farah AmmousWei ZhaoLisha LinScott M RatliffThomas H MosleyLawrence F BielakXiang ZhouPatricia A PeyserSharon L R KardiaJennifer A Smith

Published in: Clinical epigenetics (2022)

We found evidence of an association between DNA methylation and atherosclerosis at multiple vascular sites in a sample of African-Americans. Further evaluation of these potential biomarkers is warranted to deepen our understanding of the relationship between epigenetics and atherosclerosis.

Keyphrases

dna methylation
cardiovascular disease
genome wide
gene expression
copy number