Safety and Efficacy of Irradiation Boost Based on 18F-FET-PET in Patients with Newly Diagnosed Glioblastoma.

Mateusz SzylbergMaciej BlokIzabela MiechowiczIzabela WiatrowskaKarolina MakarewiczBogdan Małkowski

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Survival outcomes using our novel dose-escalation concept (total 78 Gy) were promising, even within the MGMT unmethylated subgroup. Excessive neurotoxicity was not observed, but radionecrosis was common and must be considered in future trials.

Keyphrases

newly diagnosed
current status
pet ct
positron emission tomography
open label
weight gain
computed tomography
phase iii
pet imaging
radiation induced
body mass index