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Premature atrial contractions promote local directional heterogeneities in conduction velocity vectors.

Mathijs S van SchieNawin L Ramdat MisierPayam Razavi EbrahimiAnnejet HeidaRohit K KharbandaYannick J H J TaverneNatasja M S de Groot
Published in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2023)
Local directional heterogeneity is a novel methodology to quantify local heterogeneity in CV as a possible indicator of electropathology. Intra-operative high-resolution mapping indeed revealed that LDH increased during PACs particularly at BB and PVA. Also, patients with AF already have more LDH during SR, which becomes more pronounced during PACs.
Keyphrases
  • high resolution
  • single cell
  • atrial fibrillation
  • mass spectrometry
  • growth factor
  • left atrial
  • blood flow
  • heart failure
  • tandem mass spectrometry
  • gene therapy
  • mitral valve