HNF1A gene p.I27L is associated with early-onset, maturity-onset diabetes of the young-like diabetes in Turkey.

Selvihan BeyselNilnur EyerciFerda Alparslan PinarliMuhammed KizilgulOzgur OzcelikMustafa CaliskanErman Cakal

Published in: BMC endocrine disorders (2019)

The HNF1A gene p.I27L SNP was modestly associated with having early-onset, MODY-like diabetes in the Turkish population. HNF1A gene p.I27L SNP might contribute to age at diabetes diagnosis and family inheritance.

Keyphrases

early onset
type diabetes
genome wide
late onset
cardiovascular disease
glycemic control
copy number
genome wide identification
nuclear factor
dna methylation
gene expression
inflammatory response
transcription factor