Oral Anticoagulation Timing in Patients with Acute Ischaemic Stroke and Atrial Fibrillation.

In AF patients with severe AIS, early OAC use before the guideline-recommended days appeared to increase the risk of bleeding events, although the OAC initiation time seemed not to affect the risk of serious vascular events. The optimal severity-specific timing for OAC initiation after AIS requires further evaluation.