Leptin and NGF in saliva of patients with diabetes mellitus type 2: A pilot study.

Asta TvarijonaviciuteCandela CastilloJose J CeronSilvia Martinez-SubielaFernando TeclesPia López-Jornet

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)

This pilot study indicates that salivary leptin is increased in patients with T2D being positively correlated with insulin and pro-inflammatory cytokines and should be further explored as a non-invasive biomarker of T2D. In addition, salivary NGF was positively correlated with pro-inflammatory cytokines and further studies should be performed to evaluate whether it could be useful to detect diabetic neuropathy in T2D patients.

Keyphrases

type diabetes
end stage renal disease
ejection fraction
growth factor
newly diagnosed
anti inflammatory
glycemic control
peritoneal dialysis
patient reported outcomes
insulin resistance
adipose tissue
wound healing