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Characteristics and predictive value for graft fibrosis of the complement-binding capacity of donor-specific human leukocyte antigen antibodies after pediatric liver transplantation.

Kazuaki TokodaiShigehito MiyagiWataru NakanishiRyuichi NishimuraAtsushi FujioMasafumi GotoMichiaki UnnoTakashi Kamei
Published in: Pediatric transplantation (2019)
The association between anti-DR DSA and liver fibrosis, which was supported in this cohort, was not strengthened but rather impaired when accounting for complement-binding capacity due to low positive detection. Further studies of the association between complement-binding anti-DQ DSA and histological findings in LT are needed.
Keyphrases
  • liver fibrosis
  • endothelial cells
  • dna binding
  • binding protein
  • induced pluripotent stem cells
  • young adults
  • loop mediated isothermal amplification
  • celiac disease
  • childhood cancer