Characteristics and predictive value for graft fibrosis of the complement-binding capacity of donor-specific human leukocyte antigen antibodies after pediatric liver transplantation.
Kazuaki TokodaiShigehito MiyagiWataru NakanishiRyuichi NishimuraAtsushi FujioMasafumi GotoMichiaki UnnoTakashi KameiPublished in: Pediatric transplantation (2019)
The association between anti-DR DSA and liver fibrosis, which was supported in this cohort, was not strengthened but rather impaired when accounting for complement-binding capacity due to low positive detection. Further studies of the association between complement-binding anti-DQ DSA and histological findings in LT are needed.