The role of molecular diagnosis in anaphylactic patients with dual or triple-sensitization to Hymenoptera venoms.
Mohammad Hassan BemanianRaheleh Shokouhi ShoormastiSaba ArshiMahsa JafariSima ShokriMorteza FallahpourMohammad NabaviFatemeh ZaremehrjardiPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2024)
The molecular diagnosis of IgE-sensitization to Hymenoptera venoms can be valuable, especially in patients who show dual or triple-sensitization in skin tests, as the ALEX results revealed mono and double-sensitization to Hymenoptera venoms in 22 and 6 patients, respectively. Regarding the high cost and adverse reactions of venom immunotherapy, especially for two or three venoms, incorporating the molecular diagnosis alongside skin tests for accurate diagnosis of the culprit venom could help decrease costs for patients.