Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis.
Chun Shing KwokMuhammad RashidRhys BeynonDiane BarkerAshish PatwalaAdrian Morley-DaviesDuwarakan SatchithanandaJames NolanPhyo Kyaw MyintIain BuchanYoon K LokeMamas A MamasPublished in: Heart (British Cardiac Society) (2016)
Data from observational studies suggests a possible association between prolonged PR interval and significant increases in atrial fibrillation, heart failure and mortality. Future prospective studies are needed to confirm the relationships reported, consider possible mechanisms and define the optimal monitoring strategy for such patients.
Keyphrases
- heart failure
- atrial fibrillation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- type diabetes
- patient reported outcomes
- risk factors
- left ventricular
- left atrial
- electronic health record
- machine learning
- oral anticoagulants
- left atrial appendage
- big data
- venous thromboembolism
- acute coronary syndrome