Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults.
Celeste PorsbjergCharlotte UlrikTina SkjoldVibeke BackerBirger LaerumSverre LehmanCrister JansonThomas SandstrømLeif BjermerBarbro DahlenBo LundbäckDora LudviksdottirUnnur BjörnsdóttirAlan AltrajaLauri LehtimäkiPaula KauppiJussi KarjalainenHannu KankaanrantaPublished in: European clinical respiratory journal (2018)
Although a minority of asthma patients suffer from severe asthma, they represent a major clinical challenge in terms of poor symptom control despite high-dose treatment, risk of exacerbations, and side effects. Novel biological treatments may benefit patients with severe asthma, but are expensive, and are only effective in appropriately targeted patients. In some patients, symptoms are driven by other factors than asthma, and all patients with suspected severe asthma ('difficult asthma') should undergo systematic assessment, in order to differentiate between true severe asthma, and 'difficult-to-treat' patients, in whom poor control is related to factors such as poor adherence or co-morbidities. The Nordic Consensus Statement on severe asthma was developed by the Nordic Severe Asthma Network, consisting of members from Norway, Sweden, Finland, Denmark, Iceland and Estonia, including representatives from the respective national respiratory scientific societies with the aim to provide an overview and recommendations regarding the diagnosis, systematic assessment and management of severe asthma. Furthermore, the Consensus Statement proposes recommendations for the organization of severe asthma management in primary, secondary, and tertiary care.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- chronic obstructive pulmonary disease
- high dose
- prognostic factors
- peritoneal dialysis
- low dose
- lung function
- cystic fibrosis
- tertiary care
- adipose tissue
- patient reported outcomes
- drug delivery
- clinical practice
- physical activity
- weight loss
- insulin resistance
- smoking cessation