Evaluation of the Association Between Serum Levels of Testosterone and Prolactin With 6- Hydroxydopamine-Induced Parkinsonism in Male Rats.
Roghaieh RazaghiHossein PiriHanieh JafariNafiseh RastgooMohammad Ali HosseiniHashem Haghdoost YazdiPublished in: Basic and clinical neuroscience (2021)
Our findings indicated that the development of 6-OHDA-induced Parkinsonism increases the serum levels of testosterone and prolactin. Increased prolactin occurred earlier and was observed in rats with less DA neuronal loss. Therefore, prolactin levels can predict the death of DA neurons before the clinical signs of PD were revealed.