Effect of angiotensin receptor blockers and angiotensin converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in dogs with heart disease.

Éva Larouche-LebelKerry A LoughranTerry HuhMark A Oyama

Published in: Journal of veterinary internal medicine (2020)

The AP profile during telmisartan treatment is associated with higher plasma Ang1-7 as compared with during ACEI. This favorable shift is potentiated in vitro by combination of ARB + rhACE2. These data support potential AP-targeting strategies and drugs in dogs with DMVD.

Keyphrases

angiotensin converting enzyme
angiotensin ii
transcription factor
pulmonary hypertension
electronic health record
cancer therapy
molecular dynamics simulations
risk assessment
drug induced
machine learning
climate change
binding protein