Regional ventilation distribution before and after laparoscopic lung parenchymal resection.

Objective. The aim of the present study was to evaluate the influence of one-sided pulmonary nodule and tumour on ventilation distribution pre- and post- partial lung resection. Approach. A total of 40 consecutive patients scheduled for laparoscopic lung parenchymal resection were included. Ventilation distribution was measured with electrical impedance tomography (EIT) in supine and surgery lateral positions 72 h before surgery (T1) and 48 h after extubation (T2). Left lung to global ventilation ratio ( F l ), the global inhomogeneity index (GI), standard deviation of regional ventilation delay (RVD SD ) and pendelluft amplitude ( A pendelluft ) were calculated to assess the spatial and temporal ventilation distribution. Main results. After surgery (T2), ventilation at the operated chest sides generally deteriorated compared to T1 as expected. For right-side resection, the differences were significant at both supine and left lateral positions ( p < 0.001). The change of RVD SD was in general more heterogeneous. For left-side resection, RVD SD was worse at T2 compared to T1 at left lateral position ( p = 0.002). The other EIT-based parameters showed no significant differences between the two time points. No significant differences were observed between supine and lateral positions for the same time points respectively. Significance. In the present study, we found that the surgery side influenced the ventilation distribution. When the resection was performed on the right lung, the postoperative ipsilateral ventilation was reduced and the right lung ratio fell significantly. When the resection was on the left lung, the ventilation delay was significantly increased.