Bridging thrombolysis improves survival rates at 90 days compared with direct mechanical thrombectomy alone in acute ischemic stroke due to basilar artery occlusion: a systematic review and meta-analysis of 1096 patients.
Keng Siang LeeIsabel SiowJohn Jy ZhangNicholas L SynConor S GillespieLinus Zh YuenGopinathan AnilCunli YangBernard Pl ChanVijay Kumar SharmaHock-Luen TeohJing MingxueKevin Soon Hwee TeoMay Zin MyintPervinder BhogalLukas MeyerStefan SchobChing-Hui SiaAnastasios MpotsarisVolker MausTommy AnderssonFabian ArnbergVamsi Krishna GontuTsong-Hai LeeBenjamin Y Q TanLeonard Leong-Litt YeoPublished in: Journal of neurointerventional surgery (2022)
In patients with AIS due to BAO, bridging IVT was associated with lower mortality rates at 90 days, compared with direct MT. There were no improved functional outcomes or increased sICH or SAH between both arms, However, patients with LAA benefited from bridging IVT, with better functional outcomes.