Hepatitis B, C and D virus infections and risk of hepatocellular carcinoma in Africa: A meta-analysis including sensitivity analyses for studies comparable for confounders.
Donatien Serge MbagaSebastien KenmoeCyprien Kengne-NdéJean Thierry Ebogo BeloboGadji MahamatJoseph Rodrigue Foe-EssombaMarie Amougou-AtsamaSerges TchatchouangInès NyebeAlfloditte Flore FeudjioGinette Irma Kame-NgasseJeannette Nina Magoudjou-PekamLorraine K M FokouDowbiss Meta-DjomsiMartin Maïdadi-FoudiSabine Aimee Touangnou-ChamdaAudrey Gaelle Daha-TchoffoAbdel Aziz Selly-NgaloumoRachel Audrey Nayang-MundoJacqueline Félicité YénguéJean Bosco Taya-FokouRaoul Kenfack-MomoEfietngab Atembeh NouraCynthia Paola Demeni EmohHervé Raoul TazokongArnol Bowo-NgandjiCarole Stéphanie SakeEtienne Atenguena OkobalembaJacky Njiki BikoiRichard NjouomSara Honorine Riwom EssamaPublished in: PloS one (2022)
In Africa, HBV/HCV coinfections and HBV, HCV, and HDV infections are associated with an increased risk of developing HCC. The implementation of large-scale longitudinal and prospective studies including healthy participants to search for early biomarkers of the risk of progression to HCC is urgently needed.