Greater Plasma Protein Adsorption on Mesoporous Silica Nanoparticles Aggravates Atopic Dermatitis.

Jin Kyeong ChoiJun-Young ParkSoyoung LeeYoung-Ae ChoiSong KwonMin Jun ShinHui-Suk YunYong Hyun JangJinjoo Kang Namkyung Kim Dongwoo KhangSang-Hyun Kim

Published in: International journal of nanomedicine (2022)

This study demonstrates the novel impact of the MSN protein corona in inducing inflammatory responses through claudin-1 downregulation and suggests useful clinical guidelines for MSN application in cosmetics and drug delivery systems.

Keyphrases

atopic dermatitis
protein protein
amino acid
binding protein
cell proliferation
signaling pathway
clinical practice
small molecule