Role of prophylactic azithromycin to reduce airway inflammation and mortality in a RSV mouse infection model.

Ricardo A MosqueraWilfredo De Jesus-RojasJames M StarkAravind YadavCindy K JonConstance L AtkinsCheryl L SamuelsTraci R GonzalesKatrina E McBethSyed S HashmiRoberto GarolaloGiuseppe N Colasurdo

Published in: Pediatric pulmonology (2018)

Prophylactic azithromycin effectively reduced weight loss, airway inflammation, cytokine levels and mortality in RSV-infected mice. These results support the rationale for future clinical trials to evaluate the effects of prophylactic azithromycin for RSV infection.

Keyphrases

respiratory syncytial virus
clinical trial
respiratory tract
weight loss
cardiovascular events
bariatric surgery
risk factors
cardiovascular disease
type diabetes
high fat diet induced
coronary artery disease
gastric bypass
body mass index
open label
obese patients
wild type