Are higher antidepressant plasma concentrations associated with fall risk in older antidepressant users?
Anouschka C PronkE P van PoelgeestL J SeppalaK J PloegmakersB H StrickerK M A SwartS C van DijkS Oliai AraghiL C P G M de GrootN M van SchoorR A A MathôtN van der VeldePublished in: European geriatric medicine (2023)
There might be an association between plasma concentrations of TCAs and the risk of falling in older users. However, these results needs to be interpreted with caution considering the small sample size and accompanying limitation of confinement to crude analyses. Therefore, these novel findings need to replicated in a larger cohort, preferably including adjustment for potential confounders and more frequent measures of plasma concentrations is needed.