Co-Aggregation and Parallel Aggregation of Specific Proteins in Major Mental Illness.
Bobana SamardžijaMaja JukovićBeti ZaharijaÉva RennerMiklos PalkovitsNicholas J BradshawPublished in: Cells (2023)
While specific proteins are capable of co-aggregating, and appear to do so in the brains of individuals with mental illness and potentially also with suicidal tendency, it is more common for such proteins to aggregate in a parallel manner, through independent mechanisms. This information aids in understanding the distribution of protein aggregates among mental illness patients and is therefore important for any future diagnostic or therapeutic approaches based on this aspect of mental illness pathology.