Acquired Esophageal Strictures in Children: Morphometric and Immunohistochemical Analyses.
Margaret H CollinsEileen S AlexanderLisa J MartinTommie M GrotjanVincent A MukkadaAmy SheilJuan P AboniaPhilip E PutnamMarc E RothenbergPublished in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society (2021)
Compared to CE, acquired ES in children show significant structural alterations, including obliterative muscularization, inflammatory cell mural infiltrates, and extracellular matrix protein deposits. Therapies targeting connective tissue expansion, mast cells, eosinophils and inflammation may be beneficial to treat ES.