Effects of nasal high flow on sympathovagal balance, sleep, and sleep-related breathing in patients with precapillary pulmonary hypertension.

Jens SpiesshoeferBritta BannwitzMichael MohrSimon HerkenrathWinfried RanderathPaolo SciarroneChristian ThiedemannHartmut SchneiderAndrew T BraunMichele EmdinClaudio PassinoMichael DreherMatthias BoentertAlberto Giannoni

Published in: Sleep & breathing = Schlaf & Atmung (2020)

In sleeping PH patients with OSA NHF20 but not NHF50 leads to decreased sympathetic drive likely due to washout of anatomical dead space. NHF was not effective in lowering the apnea-hypopnoea index and NHF50 was poorly tolerated.

Keyphrases

pulmonary hypertension
obstructive sleep apnea
sleep quality
pulmonary artery
physical activity
pulmonary arterial hypertension
positive airway pressure
chronic rhinosinusitis
depressive symptoms
sleep apnea
drug induced