Exogenous serotonin regulates colorectal motility via the 5-HT2 and 5-HT3 receptors in the spinal cord of rats.
H NakamoriK NaitouY SanoH ShimaokaTakahiko ShiinaYasutake ShimizuPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)
These results demonstrate that exogenous serotonin acts on 5-HT2 and 5-HT3 receptors in the lumbosacral defecation center and activates the parasympathetic nervous system to enhance colorectal motility in cooperation with noradrenaline and dopamine.