The spectrum of neurological disease associated with Zika and chikungunya viruses in adults in Rio de Janeiro, Brazil: A case series.
Ravi MehtaCristiane Nascimento SoaresRaquel Medialdea-CarreraMark Alexander EllulMarcus Tulius Texeira da SilvaAnna Rosala-HallasMarcia Rodrigues JardimGirvan BurnsideLuciana PamplonaManeesh BhojakRadhika ManoharGabriel Amorelli Medeiros da SilvaMarcus Vinicius AdrianoPatricia BrasilRita Maria Ribeiro NogueiraCarolina Cardoso Dos SantosLance TurtlePatricia Carvalho de SequeiraDavid W BrownMichael J GriffithsAna Maria Bispo de FilippisTom SolomonPublished in: PLoS neglected tropical diseases (2018)
Zika virus is associated with a wide range of neurological manifestations, including central nervous system disease. Chikungunya virus appears to have an equally important association with neurological disease in Brazil, and many patients had dual infection. To understand fully the burden of Zika we must look beyond GBS, and also investigate for other co-circulating arboviruses, particularly chikungunya.