Genetic Risk Scores for the Determination of Type 2 Diabetes Mellitus (T2DM) in North India.

Lisa Mitsuko Shitomi-JonesElizabeth C Akam David John Hunter Puneetpal Singh Sarabjit Singh Mastana

Published in: International journal of environmental research and public health (2023)

Several polymorphisms were associated with T2DM risk. PRS based on even a limited number of loci improves the prediction of the disease. This may provide a useful method for determining T2DM susceptibility for clinical and public health applications.

Keyphrases

public health
genome wide
glycemic control
type diabetes
gene expression
metabolic syndrome
mass spectrometry
skeletal muscle
copy number
adipose tissue
molecularly imprinted
insulin resistance