Login / Signup

Mitochondrial dysfunction affects hepatic immune and metabolic remodeling in patients with hepatitis B virus-related acute-on-chronic liver failure.

Yu ZhangXiao-Ling TianJie-Qun LiDong-Sheng WuQiang LiBin Chen
Published in: World journal of gastroenterology (2024)
The results indicated that bioenergetic alteration driven by hypoxia and mitochondrial dysfunction affects hepatic immune and metabolic remodeling, leading to advanced HBV-ACLF. These findings highlight a new therapeutic target for improving the treatment of HBV-ACLF.
Keyphrases
  • liver failure
  • hepatitis b virus
  • drug induced
  • combination therapy
  • replacement therapy