The effects of naloxone, diazepam, and quercetin on seizure and sedation in acute on chronic tramadol administration: an experimental study.
Samaneh NakhaeeKhadijeh FarrokhfallEbrahim Miri-MoghaddamMohsen FoadoddiniMasoumeh AskariAlireza AmirabadizadehJeffrey BrentBruno MegarbaneOmid MehrpourPublished in: Behavioral and brain functions : BBF (2021)
The combined administration of naloxone and diazepam in acute-on-chronic tramadol poisoning can effectively reduce most seizure variables compared to tramadol use alone. However, none of the treatments improved sedation levels.