Drug Reaction with Eosinophilia and Systemic Symptoms Induced by Diosmin and Hesperidin: A Case Report.

Pasita Palakornkitti Teerapong Rattananukrom

Published in: Clinical, cosmetic and investigational dermatology (2024)

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous adverse reaction which exhibits a diverse range of presentations. We described a 48-year-old man diagnosed with acute generalized exanthematous pustulosis (AGEP)-like DRESS following the administration of diosmin and hesperidin. To our knowledge, diosmin and hesperidin-induced DRESS are exceptionally rare. This aims to raise awareness of potential severe cutaneous side effects in patients taking these agents.

Keyphrases

drug induced
end stage renal disease
newly diagnosed
chronic kidney disease
adverse drug
ejection fraction
early onset
liver failure
prognostic factors
sleep quality
high glucose
emergency department
intensive care unit
diabetic rats
oxidative stress
electron transfer
climate change
patient reported outcomes