Effect of bariatric surgery on circulating and urinary mitochondrial DNA copy numbers in obesity with or without diabetes.

Mihae SeoHyoungnae KimHyunjin NohJin Seok JeonDong Won ByunSang Hyun KimHye Jeong KimKyoil SuhHyeong Kyu ParkSoon Hyo Kwon

Published in: BMJ open diabetes research & care (2021)

These results suggest that T2DM induces greater kidney mitochondrial dysfunction in patients with obesity, which can be effectively restored with bariatric surgery.

Keyphrases

bariatric surgery
weight loss
mitochondrial dna
glycemic control
type diabetes
copy number
obese patients
insulin resistance
metabolic syndrome
weight gain
high fat diet induced
cardiovascular disease
genome wide