Influence of circadian rhythm on effects induced by mechanical strain in periodontal ligament cells.

Lena I PetersJana MarciniakEric KutscheraCaio LuizErika Calvano KüchlerChristian KirschneckAndreas JägerSvenja Beisel-Memmert

Published in: Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie (2024)

Our results suggest that mechanical stress affects the molecular peripheral oscillator of PDL cells. Vice versa, the circadian rhythm also seems to partially influence the effects that mechanical stress exerts on PDL cells.

Keyphrases

induced apoptosis
cell cycle arrest
atrial fibrillation
oxidative stress
cell death
signaling pathway
heart rate
blood pressure
cell proliferation
pi k akt