Increase of arginine dimethylation correlates with the progression and prognosis of ALS.
Kensuke IkenakaNaoki AtsutaYasuhiro MaedaYuji HottaRyoichi NakamuraKaori KawaiDaichi YokoiAkihiro HirakawaAkira TaniguchiMitsuya MoritaKouichi MizoguchiHideki MochizukiKazunori KimuraMasahisa KatsunoGen SobuePublished in: Neurology (2019)
There was an enhancement of arginine dimethylation in patients with ALS, and the ADMA/l-arginine ratio predicted disease progression and prognosis in such patients.