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Increase of arginine dimethylation correlates with the progression and prognosis of ALS.

Kensuke IkenakaNaoki AtsutaYasuhiro MaedaYuji HottaRyoichi NakamuraKaori KawaiDaichi YokoiAkihiro HirakawaAkira TaniguchiMitsuya MoritaKouichi MizoguchiHideki MochizukiKazunori KimuraMasahisa KatsunoGen Sobue
Published in: Neurology (2019)
There was an enhancement of arginine dimethylation in patients with ALS, and the ADMA/l-arginine ratio predicted disease progression and prognosis in such patients.
Keyphrases
  • nitric oxide
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • amyotrophic lateral sclerosis
  • prognostic factors
  • peritoneal dialysis